The researchers identified a variation in the CCNF gene in some members of an Australian family with MND and/or FTD. When they extended the study globally, they found additional variations of the CCNF gene in other families as well as in ‘sporadic’ cases of MND and/or FTD, which are those without a family history of the diseases. This latest finding published in the prestigious journal Nature Communications suggests a common mechanism for the development of MND and FTD, and adds to a growing list of genes implicated in MND. About 10% of MND occurs in families and symptoms are indistinguishable from sporadic cases. Up to 15% of MND patients are also diagnosed with FTD.