In this study researchers from Canada attempted to transplant neuronal stem cells that have been modified to produce large amounts of VEGF. Armed with their new VEGF weaponry the cells were transplanted into SOD1 MND mice. The cells were well tolerated and significantly delayed disease onset and prolonged survival of MND mice. The researchers say that their results suggest that a treatment involving transplantation of human neuronal stem cells genetically modified to over-produce growth factors might be of value in the treatment of MND patients.
Source: International MND research update -September 2009, Dr Justin Yerbury for MNDRIA